122453-73-0

  • Product Name:Chlorfenapyr
  • Molecular Formula:C15H11BrClF3N2O
  • Purity:99%
  • Molecular Weight:407.617
Inquiry

Product Details;

CasNo: 122453-73-0

Molecular Formula: C15H11BrClF3N2O

Appearance: off-white to light brown powder with an halide odor

Buy Reliable Quality Factory Supply High Purity Chlorfenapyr 122453-73-0 In Bulk Supply

  • Molecular Formula:C15H11BrClF3N2O
  • Molecular Weight:407.617
  • Appearance/Colour:off-white to light brown powder with an halide odor 
  • Vapor Pressure:4.6E-08mmHg at 25°C 
  • Melting Point:100.5oC 
  • Refractive Index:1.559 
  • Boiling Point:443.5 °C at 760 mmHg 
  • PKA:-18.00±0.70(Predicted) 
  • Flash Point:222 °C 
  • PSA:37.95000 
  • Density:1.53 g/cm3 
  • LogP:5.45548 

Chlorfenapyr(Cas 122453-73-0) Usage

Description

Chlorfenapyr is a broad spectrum pesticide which is not approved for use in the EU, and only approved for limited applications in the US (applications for ornamental plants in greenhouses). It was originally rejected for FDA approval due to avian and aquatic toxicity. Data on human toxicity is still scarce, but it has moderate mammalian toxicity when taken orally, causing vacuolation of the nervous system in mice and rats. It is not persistent in ecosystems, and has low aqueous solubility. Chlorfenapyr can also be used as an insect-proofing agent in wool, and has been investigated for applications in malaria control.

Reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039634/ https://www3.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-129093_01-Jan-01.pdf https://sitem.herts.ac.uk/aeru/ppdb/en/Reports/136.htm https://en.wikipedia.org/wiki/Chlorfenapyr https://www.pwrc.usgs.gov/resshow/Albers/albers1.htm

Chemical Properties

Off-White Solid

Uses

Chlorfenapyr is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pes t control on cotton.

Hazard

A poison by ingestion. Moderately toxic by inhalation.

Agricultural Uses

Acaracide, Insecticide, Miticide: Severely Restricted for use in EU. Active in U.S. as a foliar spray in greenhouses for ornamental crops and target pests including mites, caterpillar pests, thrips, and fungus gnats. No food use in U.S. Used on ornamental crops in commercial greenhouses to control mites, caterpillar pests, thrips and fungus gnats. Not for food use. Not an approved substance in EU countries. Registered for use in the U.S.

Trade name

AC 303630?; CL 303630?; PHANTOM?; PIRATE? 3 F; PYLON?; SUMILARV? chlorfenapyr Chemical class: Pyrrole (Pyrazole); Organofluorine

InChI:InChI=1/C15H11BrClF3N2O/c1-2-23-8-22-13(9-3-5-10(17)6-4-9)11(7-21)12(16)14(22)15(18,19)20/h3-6H,2,8H2,1H3

122453-73-0 Relevant articles

Evaluation of the molluscicidal activities of arylpyrrole on Oncomelania hupensis, the intermediate host of Schistosoma japonicum

Dai, Jianrong,Feng, Bainian,Qu, Guoli,Xing, Yuntian,Yao, Jiakai

, (2021/10/01)

The snail Oncomelania hupensis is the on...

Application of 2-aryl substituted pyrrole compound in medicine for killing oncomelania hupensis

-

Paragraph 0144; 0146; 0150; 0152, (2019/01/08)

The invention relates to an application ...

Application of 2-aryl substituted pyrrole compound in medicine for killing biomphalarid snails

-

Paragraph 0152; 0154; 0157; 0158; 0159, (2019/01/08)

The invention relates to an application ...

NOVEL CRYSTALLINE FORM OF CHLORFENAPYR, PROCESS FOR ITS PREPARATION AND USE

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Paragraph 0068; 0069, (2018/06/06)

Provided herein are the crystalline form...

122453-73-0 Process route

formaldehyde diethyl acetal
462-95-3

formaldehyde diethyl acetal

tralopyril
122454-29-9

tralopyril

chlorfenapyr
122453-73-0

chlorfenapyr

Conditions
Conditions Yield
formaldehyde diethyl acetal; tralopyril; With trichlorophosphate; In toluene; at 97 ℃; for 0.5h;
With triethylamine; In toluene; at 97 ℃; for 5h;
92.3%
formaldehyde diethyl acetal; tralopyril; With trichlorophosphate; In toluene; at 97 ℃; for 0.5h;
With triethylamine; In toluene; at 97 ℃; for 5h;
92.3%
formaldehyde diethyl acetal; tralopyril; With trichlorophosphate; In N,N-dimethyl-formamide; toluene; at 50 ℃; for 0.5h;
With triethylamine; In water; N,N-dimethyl-formamide; toluene; at 30 - 40 ℃; for 1h;
90%
formaldehyde diethyl acetal; tralopyril; With trichlorophosphate; In N,N-dimethyl-formamide; toluene; at 35 - 53 ℃; for 0.666667h; Inert atmosphere;
With triethylamine; In N,N-dimethyl-formamide; toluene; at 35 - 45 ℃; for 2h;
formaldehyde diethyl acetal; tralopyril; With trichlorophosphate; In toluene; at 45 - 65 ℃; for 1h;
With N-ethyl-N,N-diisopropylamine; In toluene; at 40 - 50 ℃; for 1h; Reagent/catalyst;
tralopyril
122454-29-9

tralopyril

ethyl chloromethyl ether
3188-13-4

ethyl chloromethyl ether

chlorfenapyr
122453-73-0

chlorfenapyr

Conditions
Conditions Yield
tralopyril; With sodium hydroxide; at 20 ℃; for 0.333333h;
ethyl chloromethyl ether; at 60 ℃; for 2h; Reagent/catalyst; Temperature;
98%
tralopyril; With sodium hydroxide; at 20 ℃; for 0.333333h;
ethyl chloromethyl ether; at 60 ℃; for 2h; Reagent/catalyst; Temperature;
98%
In tetrahydrofuran;

122453-73-0 Upstream products

  • 122454-29-9
    122454-29-9

    tralopyril

  • 3188-13-4
    3188-13-4

    ethyl chloromethyl ether

  • 462-95-3
    462-95-3

    formaldehyde diethyl acetal

  • 6212-33-5
    6212-33-5

    2-(4-Chlorophenyl)glycine

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