What is the 2'-Deoxycytidine monohydrate?

2'-Deoxycytidine monohydrate is white crystalline powder, while it's Molecular Formula is C9H13N3O4. white crystalline powder 2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

What is the CAS number for 2'-Deoxycytidine monohydrate?

The CAS number of 2'-Deoxycytidine monohydrate is 951-77-9.

What is 2'-Deoxycytidine monohydrate (951-77-9) used for?

2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. 2'-Deoxycytidine has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion, which may make it a good candidate as an anticancer drug.

What is the 2'-Deoxycytidine monohydrate?

2'-Deoxycytidine monohydrate is white crystalline powder, while it's Molecular Formula is C9H13N3O4. white crystalline powder 2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

What is the CAS number for 2'-Deoxycytidine monohydrate?

The CAS number of 2'-Deoxycytidine monohydrate is 951-77-9.

What is 2'-Deoxycytidine monohydrate (951-77-9) used for?

2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. 2'-Deoxycytidine has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion, which may make it a good candidate as an anticancer drug.

Product classification

951-77-9

Product Name：2'-Deoxycytidine
Molecular Formula：C₉H₁₃N₃O₄
Purity：99%
Molecular Weight：227.22

Inquiry

Product Details;

CasNo： 951-77-9

Molecular Formula： C₉H₁₃N₃O₄

Appearance： white crystalline powder

Trustworthy Factory Supply High Purity 99% 2'-Deoxycytidine 951-77-9 with Efficient Shipping

Molecular Formula:C9H13N3O4
Molecular Weight:227.22
Appearance/Colour:white crystalline powder
Melting Point:209-211 °C(lit.)
Refractive Index:59 ° (C=1, H2O)
Boiling Point:497.625 °C at 760 mmHg
PKA:14.03±0.60(Predicted)
Flash Point:254.754 °C
PSA：119.83000
Density:1.733 g/cm³
LogP:-1.01690

951-77-9 Relevant articles

Synthesis of novel pyrimidine nucleoside analogues

De Napoli,Mayol,Piccialli,et al.

, p. 1401 - 1403 (1986)

Reactivity and DNA Damage by Independently Generated 2′-Deoxycytidin-N4-yl Radical

Peng, Haihui,Jie, Jialong,Mortimer, Ifor P.,Ma, Zehan,Su, Hongmei,Greenberg, Marc M.

, p. 14738 - 14747 (2021/09/18)

Oxidative stress produces a variety of r...

Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds

Mondal, Santanu,Mugesh, Govindasamy

, p. 1773 - 1780 (2019/01/10)

Halogenated nucleosides, such as 5-iodo-...

Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: A backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography

Conlon, Patrick F.,Eguaogie, Olga,Wilson, Jordan J.,Sweet, Jamie S. T.,Steinhoegl, Julian,Englert, Klaudia,Hancox, Oliver G. A.,Law, Christopher J.,Allman, Sarah A.,Tucker, James H. R.,Hall, James P.,Vyle, Joseph S.

, p. 10948 - 10957 (2019/12/23)

Oligodeoxynucleotides incorporating inte...

Identification of Flavin Mononucleotide as a Cell-Active Artificial N6-Methyladenosine RNA Demethylase

Xie, Li-Jun,Yang, Xiao-Ti,Wang, Rui-Li,Cheng, Hou-Ping,Li, Zhi-Yan,Liu, Li,Mao, Lanqun,Wang, Ming,Cheng, Liang

supporting information, p. 5028 - 5032 (2019/03/17)

N6-Methyladenosine (m6A) represents a co...

951-77-9 Process route

{5'-d(ATGGGC[¹⁵N_3,¹³_C₁-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}: {5'-d(ATGGGC[¹⁵N_3,¹³_C₁-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}

: 137608-88-9
2,2-diamino-4-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]-2,5-dihydrooxazol-5-one

: 88847-89-6
7,8-dihydro-8-oxo-2'-deoxyguanosine

: 2'-deoxyadenosine

: 951-77-9
2'-Deoxycytidine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

Conditions

Conditions	Yield
{5'-d(ATGGGC[¹⁵N_3,¹³_C₁-2'-G]GCATGAAC)-3'}{3'-d(TACCCGCCGTACAAG)-5'}; With* oxygen; sodium chloride; riboflavin; In aq. buffer; for 0.333333h; pH=7; Irradiation; With nuclease P₁; deferoxamine; ammonium acetate; zinc(II) chloride; alkaline phosphatase; In aq. buffer; at 37 ℃; for 2h; pH=5.3; Reagent/catalyst; Enzymatic reaction;

{5'-d(ATGGG(5-methyl-C)[¹⁵N_3,¹³_C₁-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}: {5'-d(ATGGG(5-methyl-C)[¹⁵N_3,¹³_C₁-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}

: 137608-88-9
2,2-diamino-4-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]-2,5-dihydrooxazol-5-one

: 88847-89-6
7,8-dihydro-8-oxo-2'-deoxyguanosine

: 2'-deoxyadenosine

: 951-77-9
2'-Deoxycytidine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine