56442-22-9
- Product Name：BENZYL 4-BENZYLOXYBENZOATE
- Molecular Formula：C21H18 O3
- Purity：99%
- Molecular Weight：318.372
Product Details;
CasNo： 56442-22-9
Molecular Formula： C21H18 O3
Wholesale Factory Supply BENZYL 4-BENZYLOXYBENZOATE 56442-22-9 with Efficient Transportation
- Molecular Formula:C21H18 O3
- Molecular Weight:318.372
- Vapor Pressure:2.86E-09mmHg at 25°C
- Melting Point:117-119°C
- Refractive Index:1.6000 (estimate)
- Boiling Point:477.2°Cat760mmHg
- Flash Point:205.6°C
- PSA：35.53000
- Density:1.167g/cm3
- LogP:4.62260
BENZYL 4-BENZYLOXYBENZOATE(Cas 56442-22-9) Usage
|
General Description |
Benzyl 4-benzyloxybenzoate is a chemical compound with the molecular formula C21H18O3. It is commonly used as a fragrance ingredient and UV filter in various cosmetic and personal care products. It is a clear, colorless liquid with a slightly sweet, floral odor. Benzyl 4-benzyloxybenzoate has also been studied for its potential pharmaceutical applications, including as an anti-inflammatory and antitumor agent. However, it is important to handle this chemical with care, as it can cause skin irritation and may be harmful if ingested or inhaled. |
InChI:InChI=1/C21H18O3/c22-21(24-16-18-9-5-2-6-10-18)19-11-13-20(14-12-19)23-15-17-7-3-1-4-8-17/h1-14H,15-16H2
56442-22-9 Relevant articles
Micellar Catalysis for Sustainable Hydroformylation
Calamante, Massimo,Dei, Filippo,Maramai, Samuele,Migliorini, Francesca,Petricci, Elena
, p. 2794 - 2806 (2021/05/03)
It is here reported a fully sustainable ...
Synthesis and evaluation of new sesamol-based phenolic acid derivatives with hypolipidemic, antioxidant, and hepatoprotective effects
Xie, Yundong,Liu, Jiping,Shi, Yongheng,Bin Wang,Wang, Xiaoping,Wang, Wei,Sun, Meng,Xu, Xinya,He, Shipeng
, p. 1688 - 1702 (2021/07/26)
The objective of this study is to synthe...
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture
Kühl, Nikos,Leuthold, Mila M.,Behnam, Mira A. M.,Klein, Christian D.
, p. 4567 - 4587 (2021/05/06)
The viral serine protease NS2B-NS3 is on...
A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays
Kühl, Nikos,Graf, Dominik,Bock, Josephine,Behnam, Mira A. M.,Leuthold, Mila-Mareen,Klein, Christian D.
supporting information, p. 8179 - 8197 (2020/09/21)
Dengue and West Nile virus are rapidly s...
56442-22-9 Process route
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-
100-39-0
benzyl bromide
-
-
99-96-7
4-hydroxy-benzoic acid
-
-
56442-22-9
benzyl 4-benzyloxybenzoate
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
92% |
|
4-hydroxy-benzoic acid;
With
potassium carbonate;
In
acetone;
at 20 ℃;
for 0.5h;
benzyl bromide;
at 20 ℃;
for 0.5h;
for 16h;
Reflux;
|
92% |
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 6h;
|
81% |
|
With
potassium carbonate;
In
acetone;
at 75 ℃;
Inert atmosphere;
|
80.23% |
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 6h;
|
76% |
|
With
potassium carbonate;
In
acetone;
for 24h;
Heating;
|
71% |
|
With
potassium carbonate;
In
methanol;
|
68% |
|
With
sodium hydride;
Yield given. Multistep reaction;
1.) DMF, RT, 15 min, 2.) overnight;
|
|
|
With
potassium hydroxide;
tetrabutylammomium bromide;
Yield given. Multistep reaction;
1.) 60 deg C, 0.1 Torr, 6 h, 2.) 40 deg C, 24 h;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
|
|
|
4-hydroxy-benzoic acid;
With
sodium hydride;
In
tetrahydrofuran;
at 0 ℃;
for 0.5h;
Inert atmosphere;
benzyl bromide;
In
tetrahydrofuran;
at 0 - 20 ℃;
|
|
|
With
potassium carbonate;
In
acetone;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
Inert atmosphere;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 48h;
|
|
|
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
|
-
-
103-83-3
N,N'-dimethylbenzylamine
-
-
100-44-7
benzyl chloride
-
-
99-96-7
4-hydroxy-benzoic acid
-
-
56442-22-9
benzyl 4-benzyloxybenzoate
| Conditions | Yield |
|---|---|
|
With
sodium iodide; potassium carbonate;
In
acetonitrile;
|
76% |
56442-22-9 Upstream products
-
100-44-7
benzyl chloride
-
99-96-7
4-hydroxy-benzoic acid
-
100-39-0
benzyl bromide
-
103-83-3
N,N'-dimethylbenzylamine
56442-22-9 Downstream products
-
1486-51-7
p-(benzyloxy)benzoic acid
-
882427-74-9
2,4-Bis-benzyloxy-6-(4-benzyloxy-benzoyloxy)-benzoic acid benzyl ester
-
874751-98-1
1-(4-benzyloxybenzoyl)-5-nitro-1H-indole
-
874752-01-9
9-benzyloxy-2-nitroisoindolo[2,1-a]indol-6-one
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