What is the 2'-Fluoro-2'-deoxyuridine?

2'-Fluoro-2'-deoxyuridine is , while it's Molecular Formula is C 9 H 11 FN 2 O 5 . A component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.

What is the CAS number for 2'-Fluoro-2'-deoxyuridine?

The CAS number of 2'-Fluoro-2'-deoxyuridine is 784-71-4.

What is 2'-Fluoro-2'-deoxyuridine (784-71-4) used for?

2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity.

What is the 2'-Fluoro-2'-deoxyuridine?

2'-Fluoro-2'-deoxyuridine is , while it's Molecular Formula is C 9 H 11 FN 2 O 5 . A component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer.

What is the CAS number for 2'-Fluoro-2'-deoxyuridine?

The CAS number of 2'-Fluoro-2'-deoxyuridine is 784-71-4.

What is 2'-Fluoro-2'-deoxyuridine (784-71-4) used for?

2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity.

Product classification

784-71-4

Product Name：2'-Fluoro-2'-deoxyuridine
Molecular Formula：C₉H₁₁FN₂O₅
Purity：99%
Molecular Weight：246.195

Inquiry

Product Details;

CasNo： 784-71-4

Molecular Formula： C₉H₁₁FN₂O₅

Buy Quality Trustworthy Manufacturer Supply 2'-Fluoro-2'-deoxyuridine 784-71-4 In Stock

Molecular Formula:C₉H₁₁FN₂O₅
Molecular Weight:246.195
Melting Point:147.0 to 153.0 °C
Refractive Index:53 ° (C=0.3, H2O)
PKA:9.39±0.10(Predicted)
PSA：104.55000
Density:1.63 g/cm³
LogP:-1.87470

784-71-4 Relevant articles

Synthesis method of 2 ’ -fluoro -2 ’ - deoxyuridine and intermediate thereof

-

Paragraph 0087-0089, (2021/11/26)

The synthesis method of 2 ’ -fluoro -2 ’...

Copper(II)nitrate catalyzed regioselective protection of primary alcohols with 4,4′-dimethoxytrityl and 2,7-dimethyl-9-phenyl xanthen-9-yl groups in nucleosides and carbohydrates

Penjarla, Srishylam,Prasad, S. Rajendra,Reddy, Dhande Sudhakar,Banerjee, Shyamapada,Penta, Santhosh,Sanghvi, Yogesh S.

, p. 232 - 247 (2018/05/14)

Regioselective protection of primary hyd...

DDQ mediated regiospecific protection of primary alcohol and deprotection under neutral conditions: Application of new p-methoxy benzyl-pixyl ether as reagent of choice for nucleoside protection

Srishylam, Penjarla,Raji Reddy,Banerjee, Shyamapada,Penta, Santhosh,Sanghvi, Yogesh S.

supporting information, p. 2588 - 2591 (2017/06/13)

A simple and efficient protocol is descr...

3-methyl uridine and 4-methyl cytidine nucleoside compound, synthetic method and its pharmaceutical use

-

Paragraph 0021; 0038, (2016/10/08)

The invention discloses a 3-methyluridin...

784-71-4 Process route

: 146954-74-7
2'-deoxy-2'-fluoro-5'-O-(4,4'-dimethoxytrityl)uridine

: 56287-17-3,69123-94-0,784-71-4
2'-deoxy-2'-fluorouridine

Conditions

Conditions	Yield
With copper(II) nitrate; In methanol; at 20 ℃; for 0.25h;	93%

: 1012080-86-2
5',3'-bis-O-4,4'-dimethoxytrityl-2'-fluoro-2'-deoxyuridine

: 56287-17-3,69123-94-0,784-71-4
2'-deoxy-2'-fluorouridine

Conditions

Conditions	Yield
With acetic acid; In methanol; water; at 80 ℃; for 6h;	58%

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