4271-30-1

  • Product Name:P-AMINOBENZAMIDE GLUTAMIC ACID
  • Molecular Formula:C12H14N2O5
  • Purity:99%
  • Molecular Weight:266.254
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Product Details;

CasNo: 4271-30-1

Molecular Formula: C12H14N2O5

Appearance: Beige crystalline powder

Trustworthy Manufacturer Supply 4271-30-1 with Safe Shipping, Buy Reliable Quality P-AMINOBENZAMIDE GLUTAMIC ACID

  • Molecular Formula:C12H14N2O5
  • Molecular Weight:266.254
  • Appearance/Colour:Beige crystalline powder 
  • Vapor Pressure:1.37E-15mmHg at 25°C 
  • Melting Point:~175 °C (dec.) 
  • Refractive Index:1.617 
  • Boiling Point:607.1 °C at 760 mmHg 
  • PKA:3.50±0.10(Predicted) 
  • Flash Point:320.9 °C 
  • PSA:129.72000 
  • Density:1.418 g/cm3 
  • LogP:1.28870 

N-(4-Aminobenzoyl)-L-glutamic acid(Cas 4271-30-1) Usage

Chemical Properties

Light Tan Waxy Solid

Uses

Marker in folate metabolism studies.

Definition

ChEBI: A dipeptide resulting from the formal condensation of the carboxylic acid group of 4-aminobenzoic acid with the amino group of L-glutamic acid.

Purification Methods

Crystallise the acid from H2O. Also purify it by dissolving 2.7g in H2O (130mL), adding aqueous NaOH to pH 5.5 and adding portionwise a solution of 0.5M CuSO4 to complete precipitation of the Cu salt. This salt is filtered off, suspended in H2O and H2S is bubbled through to precipitate CuS, filter, evaporate and recrystallise the residue from H2O. It has max (H2O) at 273nm. [Backer & Houtman Recl Trav Chim Pays-Bas 70 738, 743 1951, Beilstein 14 IV 1153.]

InChI:InChI=1/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m1/s1

4271-30-1 Relevant articles

Reactivity of conjugated and unconjugated pterins with singlet oxygen (O2(1Δg)): Physical quenching and chemical reaction

Cabrerizo, Franco M.,Laura Dantola,Petroselli, Gabriela,Capparelli, Alberto L.,Thomas, Andres H.,Braun, Andre M.,Lorente, Carolina,Oliveros, Esther

, p. 526 - 534 (2007)

Pterins (PTs) belong to a class of heter...

Effect of pterin impurities on the fluorescence and photochemistry of commercial folic acid

Dántola, M. Laura,Urrutia, M. Noel,Thomas, Andrés H.

, p. 157 - 163 (2018)

Folic acid, or pteroyl?L?glutamic acid (...

Unexpected photoactivation pathways in a folate-receptor-targetedtrans-diazido Pt(iv) anticancer pro-drug

Gandioso, Albert,Marchán, Vicente,Rovira, Anna,Sadler, Peter J.,Shi, Huayun

, p. 11828 - 11834 (2020)

A conjugate between a photoactivetrans-d...

Influence of human serum albumin on photodegradation of folic acid in solution

Vorobey, Pavel,Steindal, Arnfinn Engeset,Off, Morten Kristian,Vorobey, Alexander,Moan, Johan

, p. 817 - 822 (2006)

It has been proposed that photodegradati...

DEVELOPING A CATALYST FOR HYDROGENATION OF p-NITROBENZOYL-L-GLUTAMIC ACID

Sadykova, D. A.,Kuz'micheva, E. L.,Dmitrieva, I. I.,Abdykadyrov, A. A.,Razikov, K. Kh.

, p. 273 - 275 (1985)

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Preparation method of N-p-aminobenzoyl-L-glutamic acid

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Paragraph 0015; 0019; 0020; 0021; 0022; 0024, (2018/07/15)

The invention discloses a preparation me...

Preparation method of N (4-aminobenzoyl)-L-glutamic acid

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Paragraph 0029; 0030, (2016/10/31)

The invention provides a preparation met...

4271-30-1 Process route

Di-tert-butyl 3-fluoro,4-nitrobenzoyl-L-glutamate

Di-tert-butyl 3-fluoro,4-nitrobenzoyl-L-glutamate

N-(4-aminobenzoyl)-L-glutamic acid
4271-30-1,532-63-8

N-(4-aminobenzoyl)-L-glutamic acid

Conditions
Conditions Yield
With ammonium formate; palladium-carbon; In methanol;
99%
dimethyl p-trifluoroacetamidobenzoyl-L-glutamate
233600-78-7

dimethyl p-trifluoroacetamidobenzoyl-L-glutamate

N-(4-aminobenzoyl)-L-glutamic acid
4271-30-1,532-63-8

N-(4-aminobenzoyl)-L-glutamic acid

Conditions
Conditions Yield
With sodium hydroxide; water; In methanol; at 23 ℃; for 4h;
61%

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    folic acid

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