What is the 2'-Deoxyuridine?

2'-Deoxyuridine is White crystalline powder, while it's Molecular Formula is C9H12N2O5. White crystalline powder An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease

What is the CAS number for 2'-Deoxyuridine?

The CAS number of 2'-Deoxyuridine is 951-78-0.

What is 2'-Deoxyuridine (951-78-0) used for?

2'-Deoxyuridine is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. 2'-Deoxyuridine has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-Deoxyuridine has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate. 2'-Deoxyuridine is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses.

What is the 2'-Deoxyuridine?

2'-Deoxyuridine is White crystalline powder, while it's Molecular Formula is C9H12N2O5. White crystalline powder An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease

What is the CAS number for 2'-Deoxyuridine?

The CAS number of 2'-Deoxyuridine is 951-78-0.

What is 2'-Deoxyuridine (951-78-0) used for?

2'-Deoxyuridine is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. 2'-Deoxyuridine has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-Deoxyuridine has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate. 2'-Deoxyuridine is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses.

Product classification

951-78-0

Product Name：2'-Deoxyuridine
Molecular Formula：C₉H₁₂N₂O₅
Purity：99%
Molecular Weight：228.205

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Product Details;

CasNo： 951-78-0

Molecular Formula： C₉H₁₂N₂O₅

Appearance： White crystalline powder

Reputable Manufacturer Supply High Purity 2'-Deoxyuridine 951-78-0 with Cheapest Price

Molecular Formula:C9H12N2O5
Molecular Weight:228.205
Appearance/Colour:White crystalline powder
Melting Point:167-169 °C(lit.)
Refractive Index:52 ° (C=1, 1mol/L NaOH)
Boiling Point:370.01°C (rough estimate)
PKA:pKa 9.3(H2O t = 25) (Uncertain)
PSA：104.55000
Density:1.533 g/cm³
LogP:-1.82270

951-78-0 Relevant articles

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir

Birmingham, William R.,Burke, Ashleigh J.,Charnock, Simon J.,Crawshaw, Rebecca,Finnigan, James D.,Green, Anthony P.,Holgate, Gregory M.,Lovelock, Sarah L.,Muldowney, Mark P.,Rowles, Ian,Thorpe, Thomas W.,Turner, Nicholas J.,Young, Carl,Zhuo, Ying,Zucoloto Da Costa, Bruna

supporting information, p. 3761 - 3765 (2022/03/15)

The Covid-19 pandemic highlights the urg...

Reactivity and DNA Damage by Independently Generated 2′-Deoxycytidin-N4-yl Radical

Peng, Haihui,Jie, Jialong,Mortimer, Ifor P.,Ma, Zehan,Su, Hongmei,Greenberg, Marc M.

, p. 14738 - 14747 (2021/09/18)

Oxidative stress produces a variety of r...

Thermodynamic Reaction Control of Nucleoside Phosphorolysis

Kaspar, Felix,Giessmann, Robert T.,Neubauer, Peter,Wagner, Anke,Gimpel, Matthias

supporting information, p. 867 - 876 (2020/01/24)

Nucleoside analogs represent a class of ...

Dehalogenation of Halogenated Nucleobases and Nucleosides by Organoselenium Compounds

Mondal, Santanu,Mugesh, Govindasamy

, p. 1773 - 1780 (2019/01/10)

Halogenated nucleosides, such as 5-iodo-...

951-78-0 Process route

: 34279-87-3
1-(O³,O⁵-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-5-bromo-4-trimethylsilanyloxy-1H-pyrimidin-2-one

: 75-24-1
trimethylaluminum

: 951-78-0,63844-76-8
2'-deoxyuridine

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

Conditions

Conditions	Yield
With water; ammonium chloride; triphenylphosphine; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, reflux, 12 h, 2) MeOH, reflux, 3 h;

: 54-42-2,162239-35-2
5-Iodo-2'-deoxyuridine

: 951-78-0,63844-76-8
2'-deoxyuridine

: 59-14-3,723-73-9
5-bromo-2'-deoxyuridine